Ascentis® Silica HPLC columns for the classic use in normal phase HPLC.

• High purity, type B silica for inertness, reproducibility, and stability
• Modern bonding process optimises bonded phase coverage and maximises stability, while minimizing bleed and unwanted secondary interactions
• Compatible with LC-MS and all of today's sensitive instruments and methods
• Scalable sensitivity from analytical to preparative
• High surface area silica for high preparative loading capacity
• Impurity: <5 ppm metals

The right structure of the silica surface, as opposed to the flexible nature of bonded phases, allows it to distinguish between molecules with different molecular shape that may have the same hydrophobicity. Ascentis® Si columns provide a high-loading capacity and operate in both normal phase and HILIC modes.

Ascentis® bonded phases have a wide range of selectivities. It is likely that one or more Ascentis® phase will accomplish any small molecule HPLC separation. Packed in micro- to preparative hardware dimensions, Ascentis® products cover all HPLC application areas, including the most sensitive trace-level analyses.