Specifications

Bal.:
25 kg
Sekvence:
4283
Environmentally Preferable:

Specifications

Specification Test Results

Assay (Acidim) calc. a.d.s.:
99,0 -100,5 %
Identity according to Pharmacopoeias:
Passes test
pH sol. 10 %:
10,0 - 11,5
pH sol. 5 %:
10,0 - 11,5
Melting range :
168 - 172 ºC
Maximum limit of impurities
ABS
at λ a 290 nm, 1 cm 40% sol. in H2O:
0,1
Appearance of solution:
passes test
Insoluble matter in H2O:
0,025 %
Loss on drying at 105 °C:
0,5 %
Residue on ignition (as SO4):
0,1 %
Chloride (Cl):
0,003 %
Microbial Limits:
2,5 UI/g
Bacterial endotoxins:
1000 cfu/g
Total Aerobic Microbial Count (TAMC):
100 cfu/g
Total combined yeast and moulds (TYMC):
passes test
Residual solvents (Ph.Eur/USP):
1,0 %
Related substances (T.L.C.):
0,001 %
Heavy metals (as Pb):
0,001 %
Fe:
0,001 %
Elemental impurities (ICH Q3D)
Class 1
Cd:
0,5 ppm
PB:
0,5 ppm
As:
1 ppm
Hg:
1,5 ppm
Class 2A
Co:
5 ppm
V:
10 ppm
Ni:
20 ppm
Class 2B
Tl:
2 ppm
Au:
10 ppm
Pd:
10 ppm
Ir:
10 ppm
Os:
10 ppm
Rh:
10 ppm
Ru:
10 ppm
Se:
15 ppm
Ag:
15 ppm
Pt:
10 ppm
Class 3
Li:
55 ppm
Sb:
120 ppm
Ba:
140 ppm
Mo:
25 ppm
Cu:
250 ppm
Sn:
600 ppm
C:
25 ppm

Specification Test Results

About this item

Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol(tris), Tromethamine, Tris(hydroxymethyl)methylamine, 2-Amino-2-(hydroxymethyl)propane-1,3-diol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Trizma(R) base, TRIS base, THAM

Boiling Pt:219,..220 °C

Storage Temperature:Room Temperature

EINECS:201-064-4

CAS Number:77-86-1

Formula:NH₂C(CH₂OH)₃

MDL Number:MFCD00004679