- Druh protilátky:Primární
- Název antigenu:V-type proton ATPase subunit B, kidney isoform
- Symbol antigenu:ATP6V1B1
- Klonovalita:Polyclonal
- Spojení:Unconjugated
- Hostitel:Rabbit
- Imunochemie:Yes
- ImunoFluorescence:Yes
- Reaktivita:Human
- Western blot:Yes
- Epitop:Amino Acid Range = 284-310
- Formulář:Liquid
- Identifikační číslo genu:P15313
- Synonyma antigenu:ATP6V1B1
- Modifikace:None
- Skladovací pufr:Supplied in PBS with 0,09% (W/V) sodium azide
- Molekulární hmotnost:57 kDa
- Skladovací teplota:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Koncentrace:0,5 mg/ml
- Transportní teplota:4 °C
- Imunogen:This ATP6V1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-310 amino acids from the Central region of human ATP6V1B1.
- Čištění:This antibody is purified through a protein A column, followed by peptide affinity purification.
- Rozměry protilátky:400 µl
- Bal.:400 µl
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq].
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50.
Type: Primary
Antigen: ATP6V1B1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human