Specifikace
- Druh protilátky:Primární
- Název antigenu:SCN2B
- Klonovalita:Polyclonal
- Spojení:Alexa Fluor® 750
- Hostitel:Rabbit
- Imunochemie:Yes
- ImunoFluorescence:Yes
- Izotyp:IgG
- Epitop:65-180/215
- Formulář:Liquid
- Synonyma antigenu:Sodium channel voltage gated type II beta polypeptide|SCN2B_HUMAN|Scn2b|Scn 2b|Sodium channel subunit beta 2|Sodium channel subunit beta-2|Sodium channel beta 2 subunit|Neuronal voltage gated sodium channel beta 2 subunit|Sodium channel voltage gated type II beta
- Modifikace:Unmodified
- Skladovací pufr:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molekulární hmotnost:21 kDa
- Skladovací teplota:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentrace:1 µg/µl
- Transportní teplota:4 °C
- Imunogen:KLH conjugated synthetic peptide derived from human SCN2B
- Testované aplikace:ICC
- Čištění:Purified by Protein A
- Typ balení:Vial
- Bal.:100 µl
Specifikace
O tomto produktu
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
Type: Primary
Antigen: SCN2B
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 65-180/215
Host: Rabbit
Isotype: IgG
Reactivity: