Anti-CDKN1A Thr57 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-5238R-A750
Supplier: Bioss
Specifications
- Druh protilátky:Primární
- Název antigenu:CDKN1A Thr57
- Klonovalita:Polyclonal
- Spojení:Alexa Fluor® 750
- Hostitel:Rabbit
- Imunochemie:Yes
- ImunoFluorescence:Yes
- Izotyp:IgG
- Reaktivita:Human,Rat,Mouse
- Western blot:Yes
- Formulář:Liquid
- Identifikační číslo genu:1026
- Synonyma antigenu:MDA-6|WAF1|P21|CAP20|p21CIP1|SDI1|Cyclin-dependent kinase inhibitor 1|CDK-interacting protein 1|MDA6|CDKN1A|CIP1|Melanoma differentiation-associated protein 6|CDKN1|PIC1
- Modifikace:Phosphorylation (Thr57)
- Skladovací pufr:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molekulární hmotnost:18 kDa
- Skladovací teplota:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentrace:1 µg/µl
- Transportní teplota:4 °C
- Imunogen:KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr57 [TE(p-T)PL]
- Testované aplikace:ICC
- Čištění:Purified by Protein A
- Typ balení:Vial
- Bal.:100 µl
Specifications
About this item
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Type: Primary
Antigen: CDKN1A Thr57
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat