- Druh protilátky:Primární
- Název antigenu:C4 binding protein
- Klonovalita:Polyclonal
- Spojení:Alexa Fluor® 647
- Hostitel:Rabbit
- Imunochemie:Yes
- ImunoFluorescence:Yes
- Izotyp:IgG
- Reaktivita:Human
- Western blot:Yes
- Epitop:1-100/252
- Formulář:Liquid
- Synonyma antigenu:PRP|OTTHUMP00000034375|C4b-binding protein beta chain|OTTHUMP00000034288|OTTHUMP00000034289|OTTHUMP0000003474|Complement component 4-binding protein beta|Complement component 4 binding protein beta chain|C4BP|Complement component 4 binding protein beta|C4b binding protein beta chain|C4BPB_HUMAN|Proline rich protein|C4BPB
- Modifikace:Unmodified
- Skladovací pufr:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molekulární hmotnost:26 kDa
- Skladovací teplota:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentrace:1 µg/µl
- Transportní teplota:4 °C
- Imunogen:KLH conjugated synthetic peptide derived from human C4 binding protein
- Testované aplikace:ICC
- Čištění:Purified by Protein A
- Typ balení:Vial
- Bal.:100 µl
C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
Type: Primary
Antigen: C4 binding protein
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 647
Public Immunogen Range: 1-100/252
Host: Rabbit
Isotype: IgG
Reactivity: Human