Anti-ICAM1 Mouse Antibody [clone: 15.2]
70-0549-U100
- Druh protilátky:Primární
- Název antigenu:Intercellular Adhesion molecule 1
- Symbol antigenu:ICAM1
- Klon:15.2
- Spojení:Unconjugated
- Průtoková cytometrie:Yes
- Hostitel:Mouse
- Imunochemie:Yes
- Izotyp:IgG1
- Reaktivita:Human
- Western blot:Yes
- Neutralizace:Yes
- Identifikační číslo genu:3383
- Synonyma antigenu:ICAM-1|major group rhinovirus receptor|human rhinovirus receptor|BB2|cell surface glycoprotein P3.58|intercellular adhesion molecule 1|P3.58
- Skladovací teplota:Store undiluted at 2-8°C, protect from light, do not freeze.
- Testované aplikace:Flow Cytometry
- Rozměry protilátky:100 µg
- Bal.:100 µG
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).
The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.