Human Recombinant IL-31 (Animal free) (from E. coli)

Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation.

High quality
Low endotoxin
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In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier's disease. TGF-α is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
E. coli
Druhy:
Human
Podmínky uskladnění:
−20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤0.1
Biologická aktivita:
Bioactivity assay: STAT3 Activation in U-87 MG cells, ED50 ≤Detectable at ≤ 25 ng/ml, bioactivity ≥0
Identifikační číslo genu:
Q6EBC2
Pokyny pro rekonstituce:
Sterile water at 0,1 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
Y
Proteinová synonyma:
IL-31|Interleukin-31
Název proteinu/peptidu:
IL31
Čistota:
≥95%
Molekulární hmotnost:
15,8 kDa
Sekvence:
SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
Úroveň endotoxinů:
Low
Formulace:
20 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
Bez nukleáz:
N
Třída:
RUO
Transportní teplota:
RT
Testované aplikace:
Bioassay