Human Recombinant VEGF-121 (from E. coli)

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

High quality
Low endotoxin
Affordable

: This product is for research use only and is not for use in humans.

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
E. coli
Druhy:
Human
Podmínky uskladnění:
–20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤0,1
Biologická aktivita:
Bioactivity Assay: HUVEC proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
Identifikační číslo genu:
P15692-9
Pokyny pro rekonstituce:
Sterile water at 0,1 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
Y
Proteinová synonyma:
glioma-derived endothelial cell mitogen|VEGF-A|VPF
Název proteinu/peptidu:
VEGF-121 (AF)
Čistota:
≥95%
Molekulární hmotnost:
14,2/28,4 kDa
Sekvence:
MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR
Úroveň endotoxinů:
Low
Formulace:
0,1% Trifluoroacetic acid (TFA)
Bez nukleáz:
N
Třída:
RUO
Transportní teplota:
RT
Testované aplikace:
Bioassay