About this item
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
- High quality
- Low endotoxin
- Affordable
Animal-free proteins are ideal for researchers concerned about the ever-present risk of contaminating human proteins or trace growth factors from FBS and animal-derived ingredients typically used in standard recombinant protein production techniques.
Specifications
- Spojení:Unconjugated
- Proteinový podtyp:Cytokine
- Typ proteinu/peptidu:Recombinant
- Zdroj:E. coli
- Druhy:Dog
- Podmínky uskladnění:−20 °C
- Obsah endotoxinů:Endotoxin LAL (EU/µg) ≤0.1
- Biologická aktivita:Bioactivity assay: TF-1 cell proliferation, ED50 ≤15 ng/ml, bioactivity ≥6,7×10⁴ units/mg
- Identifikační číslo genu:P48749
- Pokyny pro rekonstituce:Sterile water at 0,1 mg/ml
- Bez obsahu endotoxinů:N
- Bez nosiče:Y
- Bez obsahu proteázy:N
- Bez obsahu živočichů:Y
- Proteinová synonyma:MGI-1GM|CSF-2|Pluripoietin-α
- UniProtKB:P48749
- Název proteinu/peptidu:GM-CSF
- Čistota:≥95%
- Molekulární hmotnost:14,4 kDa
- Sekvence:MAPTRSPTLV TRPSQHVDAI QEALSLLNNS NDVTAVMNKA VKVVSEVFDP EGPTCLETRL QLYKEGLQGS LTSLKNPLTM MANHYKQHCP PTPESPCATQ NINFKSFKEN LKDFLFNIPF DCWKPVKK
- Úroveň endotoxinů:Low
- Formulace:10 mM sodium phosphate, pH 7,5
- Bez nukleáz:N
- Třída:RUO
- Transportní teplota:RT
- Testované aplikace:Bioassay