Human Recombinant LIF (Animal free) (from E. coli)

O tomto produktu

Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Human LIF may also be an important factor during human embryonic stem cell (hESC) self-renewal, pluripotency, and embryonic implantation.

High Quality
Low Endotoxin
Affordable

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

Caution: For research use only.

Specifikace

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
HEK293 cells
Druhy:
Human
Podmínky uskladnění:
–20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤0,1
Biologická aktivita:
Bioactivity assay: TF-1 cell proliferation, ED50 ≤0,2 ng/ml, Bioactivity ≥5,0×10⁶ units/mg
Identifikační číslo genu:
P15018
Pokyny pro rekonstituce:
Sterile 10 mM acetic acid at 0.1 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
Y
Proteinová synonyma:
Leukocyte Inhibitory Factor
Název proteinu/peptidu:
LIF
Čistota:
≥95%
Molekulární hmotnost:
19,8 kDa
Sekvence:
MSPLPITPVN ATCAIRHPCH NNLMNQIRSQ LAQLNGSANA LFILYYTAQG EPFPNNLDKL CGPNVTDFPP FHANGTEKAK LVELYRIVVY LGTSLGNITR DQKILNPSAL SLHSKLNATA DILRGLLSNV LCRLCSKYHV GHVDVTYGPD TSGKDVFQKK KLGCQLLGKY KQIIAVLAQA F
Úroveň endotoxinů:
Low
Formulace:
0,1% Trifluoroacetic Acid (TFA)
Bez nukleáz:
N
Třída:
RUO
Transportní teplota:
Ice pack
Testované aplikace:
Bioassay