TSKgel® UP-SW2000 columns are designed for the analysis of small proteins, peptides and oligonucleotides. The columns are packed with 2 μm silica-based beads shielded with a hydrophilic diol-type bonded phase that prevents the silica surface from interacting with protein samples.

• Higher resolution, improved peak shape and increased efficiency
• Robust, reproducible results that are easily transferrable between UHPLC and HPLC systems
• Calibration range (proteins): 1000 - 1,5×10⁵ Da (globular proteins)
• Virtual absence of non specific interaction

TSKgel® UP-SW2000 columns feature the same pore size as the TSKgel® SuperSW2000 columns. Hence methods developed using TSKgel® SuperSW2000 columns can easily be transferred to TSKgel® UP-SW2000 columns on conventional HPLC systems as well as on UHPLC systems.

TSKgel® UP-SW2000 columns offer superior reproducibility injection-to-injection, from column-to-column within the same lot and from lot-to-lot. %RSD values for peak parameters including retention times, area peak height, peak asymmetry, and theoretical plate count demonstrate the exceptional reproducibility of these columns.

Both guard columns can be connected to either analytical column. The DC guard column can be directly connected to the analytical column without tubing between the two columns. A male-type outlet endfitting on the guard column enables the direct connection to the screw-type endfitting of the analytical column.