Human Recombinant IL-6 (from E. coli)

Supplier: Shenandoah Biotechnology

Certificates

Supplier: Shenandoah Biotechnology

About this item

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6Rα and gp130.

High quality
Low endotoxin
Affordable

IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines. Human IL-6 is active on mouse and rat cells.

These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.

Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

Caution: For research use only.

Specifications

Spojení:
Unconjugated
Proteinový podtyp:
Cytokine
Typ proteinu/peptidu:
Recombinant
Zdroj:
E. coli
Druhy:
Human
Podmínky uskladnění:
−20 °C
Obsah endotoxinů:
Endotoxin LAL (EU/µg) ≤1
Biologická aktivita:
Bioactivity assay: B9 cell proliferation, ED50 ≤0,025 ng/ml, bioactivity ≥4,0×10⁷ units/mg
Identifikační číslo genu:
P05231
Pokyny pro rekonstituce:
Sterile water at 0,1 mg/ml
Bez obsahu endotoxinů:
N
Bez nosiče:
Y
Bez obsahu proteázy:
N
Bez obsahu živočichů:
N
Proteinová synonyma:
IFN-β2|HSF|BSF-2|B-cell differentiation factor|MGI-2
UniProtKB:
P05231
Název proteinu/peptidu:
IL-6
Čistota:
≥97%
Molekulární hmotnost:
21 kDa
Sekvence:
MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Úroveň endotoxinů:
Low
Formulace:
10 mM sodium phosphate, pH 7,5
Bez nukleáz:
N
Třída:
RUO
Transportní teplota:
RT
Testované aplikace:
Bioassay