M. tuberculosis Recombinant NAD Kinase (from E. coli)
Catalog # PRSI90-365
Supplier: ProSci Inc.
CAS Number:
Specifications
- Bal.:50 µG
- Typ enzymu:Recombinant
- Zdroj:E. coli
- Druhy:M. tuberculosis
- Sekvence značek:His Tag
- Podmínky uskladnění:Stable for at least 6 months after receipt when stored at –80 °C.
- Název enzymu:NAD Kinase
- Aktivita enzymu:~1.2 U/mg protein. (Substrate: NAD (+ ATP))
~3.8 U/mg protein. (Substrate: NAD (+ poly(P))
One unit is defined as the amount of enzyme that synthesizes 1umol nicotinamide adenine dinucleotide phosphate (NADP) per min. - Čistota:>98% (SDS-PAGE)
- Formulace:Liquid, In 10 mM TRIS at pH 8.0, containing 1 mM MgCl₂, 0.5 mM EDTA, 1 mM DTT and 1 mM PMSF.
Specifications
About this item
NAD kinase catalyses the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+.
Fusion-Tag: His Tag
This recombinant proteins is for research use only.