Specifikace
- Bal.:50 µG
- Typ enzymu:Recombinant
- Zdroj:E. coli
- Druhy:Human
- Sekvence značek:His Tag
- Podmínky uskladnění:Stable for at least 6 months after receipt when stored at –80 °C.
- Název enzymu:NAPRTase
- Aktivita enzymu:~0,27 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1 umol nicotinic acid mononucleotide (NaMN) per min.
- Čistota:>98% (SDS-PAGE)
- Formulace:Liquid, In 50 mM HEPES/KOH pH 7,5 containing 300 mM potassium chloride and 10 mM DTT.
Specifikace
O tomto produktu
Human nicotinate phosphoribosyltransferase (NAPRTase) is localised in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
Fusion-Tag: His Tag
This recombinant proteins is for research use only.