Human recombinant Carboxypeptidase E (from Cells)
Katalogové číslo PRSI91-840
Dodavatel: ProSci Inc.
Číslo CAS:
Specifikace
- Bal.:50 µG
- Typ enzymu:Recombinant
- Zdroj:Cells
- Druhy:Human
- Sekvence značek:C-6 His tag
- Podmínky uskladnění:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Název enzymu:Carboxypeptidase E
- Čistota:>95% as determined by reducing SDS-PAGE
- Molekulární hmotnost:47.1 kD
- Sekvence:Arg42-Ser453
- Formulace:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl,1 mM ZnCl₂, 10% Glycerol,pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Testované aplikace:Bioassay
Specifikace
O tomto produktu
The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.