Specifications

Bal.:
50 µG
Typ enzymu:
Recombinant
Zdroj:
Cells
Druhy:
Human
Sekvence značek:
C-6 His tag
Podmínky uskladnění:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
Název enzymu:
Isocitrate Dehydrogenase
Čistota:
>95% as determined by reducing SDS-PAGE
Molekulární hmotnost:
47.7 kD
Sekvence:
Met1-Leu414
Formulace:
Supplied as a 0.2 µm filtered solution of PBS. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Testované aplikace:
Bioassay

Specifications

About this item

Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.