Human recombinant proteinase 3 (from cells)
Catalog # PRSI91-542
Dodavatel: ProSci Inc.
Číslo CAS:
Specifikace
- Bal.:50 µG
- Typ enzymu:Recombinant
- Zdroj:Cells
- Druhy:Human
- Sekvence značek:C-6 His tag
- Podmínky uskladnění:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Název enzymu:Proteinase 3
- Čistota:>95% as determined by reducing SDS-PAGE
- Molekulární hmotnost:25.64 kD
- Sekvence:Ala26-Arg249
- Formulace:Supplied as a 0.2 µm filtered solution of 10 mM TrisHCl, 150 mM NaCl, 10% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Testované aplikace:Bioassay
Specifikace
O tomto produktu
Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.