Specifications
- Bal.:50 µG
- Typ enzymu:Recombinant
- Zdroj:E. coli
- Druhy:Human
- Sekvence značek:C-6 His tag
- Podmínky uskladnění:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Název enzymu:Carbonic Anhydrase 4
- Čistota:>95% as determined by reducing SDS-PAGE
- Molekulární hmotnost:31.43 kD
- Sekvence:Ala19-Lys283
- Formulace:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 100 mM NaCl, pH 8.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Testované aplikace:Bioassay
Specifications
About this item
Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.