Specifications
- Bal.:50 µG
- Typ proteinu/peptidu:Recombinant
- Zdroj:E. coli
- Druhy:Human
- Podmínky uskladnění:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Proteinová synonyma:Paired helical filament-tau|Tau-F|MAPTL|MTBT1|TAU and MAPT|Microtubule-associated protein tau|Neurofibrillary tangle protein
- Název proteinu/peptidu:MAPT-F
- Čistota:> 95% as determined by reducing SDS-PAGE
- Molekulární hmotnost:45.85 kD
- Sekvence:Met1-Leu441
- Formulace:Lyophilized from a 0.2 um filtered solution of PBS，pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Testované aplikace:Bioassay
Specifications
About this item
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
This recombinant protein can be used for biological assays. For research use only.