Specifikace
- Druh protilátky:Primární
- Název antigenu:Conserved Helix-loop-helix Ubiquitous Kinase
- Symbol antigenu:CHUK
- Klonovalita:Polyclonal
- Spojení:Alexa Fluor® 488
- Hostitel:Rabbit
- Imunochemie:Yes
- Izotyp:IgG
- Reaktivita:Human,Rat,Mouse
- Křížová adsorbce:No
- Formulář:liquid
- Identifikační číslo genu:1147
- Synonyma antigenu:NFKBIKA|IKBKA|IKK-alpha|IKK1|IKKA|TCF16
- Modifikace:phospho-Tyr463
- Skladovací pufr:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Skladovací teplota:Store at 4°C for 12 months
- Koncentrace:1 μg/μl
- Transportní teplota:4°C
- Čištění:Purified by Protein A
- Bal.:100 µl
Specifikace
O tomto produktu
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CHUK
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype:
Reactivity: