Anti-LIG4 Rabbit Polyclonal Antibody (Cy5®)
Katalogové číslo BOSSBS-1677R-CY5
Dodavatel: Bioss
Specifikace
- Druh protilátky:Primární
- Název antigenu:DNA Ligase 4
- Symbol antigenu:LIG4
- Klonovalita:Polyclonal
- Spojení:Cy5®
- Hostitel:Rabbit
- Imunochemie:Yes
- Izotyp:IgG
- Reaktivita:Human,Rat,Mouse
- Křížová adsorbce:No
- Formulář:liquid
- Identifikační číslo genu:3981
- Synonyma antigenu:LIG4S
- Skladovací pufr:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Skladovací teplota:Store at 4°C for 12 months
- Koncentrace:1 μg/μl
- Transportní teplota:4°C
- Imunogen:60-110/911
- Čištění:Purified by Protein A
- Bal.:100 µl
Specifikace
O tomto produktu
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: LIG4
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat