The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: C146/634
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
- Catalog No:
- BNC940634-100
- BNC940634-500
- Symbol antigenu:
- MCAM
- MCAM
- Název antigenu:
- CD146 / MCAM / MUC18 / Mucin 18
- CD146 / MCAM / MUC18 / Mucin 18
- Druh protilátky:
- Primární
- Primární
- Klonovalita:
- Monoclonal
- Monoclonal
- Spojení:
- CF® 594
- CF® 594
- Klon:
- Clone C146/634
- Clone C146/634
- Reaktivita:
- Human
- Human
- Hostitel:
- Mouse
- Mouse
- Identifikační číslo genu:
- 599039
- 599039
- Izotyp:
- IgG1 kappa
- IgG1 kappa
- Imunochemie:
- Yes
- Yes
- ImunoFluorescence:
- Yes
- Yes
- Koncentrace:
- 0,1 mg/ml
- 0,1 mg/ml
- Skladovací pufr:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Chemicals
: VWR Collection
: VWR Collection