Anti-FADD Mouse Monoclonal Antibody [clone: 1F7]
ENZOADIAAM212E
- Druh protilátky:Primární
- Název antigenu:Fas-associated protein with death domain
- Symbol antigenu:FADD
- Klonovalita:Monoclonal
- Klon:1F7
- Spojení:Unconjugated
- Hostitel:Mouse
- Izotyp:IgG1
- Western blot:Yes
- Sekvence:02
- Formulář:Liquid
- Synonyma antigenu:FAS-associated death domain-containing protein|MORT1|MGC8528|GIG3
- Skladovací pufr:PBS containing 50% glycerol
- Skladovací teplota:–20 °C
- Transportní teplota:Shipped on blue ice
- Imunogen:Recombinant human FADD
- Čištění:Purified by Protein A affinity chromatography
- Rozměry protilátky:100 μg
- Bal.:100 µG
Fas-associating death domain containing protein (FADD)/MORT1 serves as a signal transducer of Fas-induced apoptosis.
- Dilution range: 1 µg/ml, ECL for Western blot
- Detects a band of ~28 kDa by Western blot
Through its amino-terminal death effector domain (DED), FADD binds to cytosolic proteins such as TRADD, a cytosolic death domaincontaining protein that asssociates with the cytosolic portion of TNF receptor, or MACH/FLICE/caspase-8, a protease with sequence homology to ICE-CED-3 protease family, in order to transduce the death signal.
Type: Primary
Antigen: Fas-Associated protein with Death Domain
Clonality: Monoclonal
Clone: 1F7
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse