Specifications
- Název antigenu:NLR family, CARD domain containing 4
- Symbol antigenu:NLRC4
- Klonovalita:Polyclonal
- Hostitel:Rabbit
- Izotyp:IgG
- Reaktivita:Human,Rat,Mouse
- Western blot:Yes
- Formulář:Lyophilized
- Identifikační číslo genu:58484
- Synonyma antigenu:CLANA|AIFEC|CLAN|FCAS4|CARD12|CLAN1|CLR2.1|CLANC|IPAF|CLAND|CLANB
- UniProtKB:Q9NPP4
- Skladovací teplota:At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
- Imunogen:A synthetic peptide corresponding to a sequence at the C-terminus of human CARD12 (838-874aa KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
- Čištění:Immunogen affinity purified.
- Rozměry protilátky:100 μg / vial
- Bal.:100 µG
Specifications
About this item
Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human;Mouse;Rat.
NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Tested Species: In-house tested species with positive results.
Other applications have not been tested.
Optimal dilutions should be determined by end users.