CypHer5E is a red-excitable, pH-sensitive cyanine dye derivative that is minimally fluorescent at a basic pH and maximally fluorescent at an acidic pH.

• Generic technology can be coupled to any receptor or epitope tag antibody
• Monitors any neutral to acidic event
• Simple fluorescence intensity increase

It is well suited to report the movement of a receptor from the cell surface into acidic endosomes upon agonist stimulation.