Hledali jste: Streptozocin

Supplier: Apollo Scientific

Potent methylating agent for DNA

Supplier: ENZO LIFE SCIENCES

Widely used diabetes inducer in rodents. Inhibition of β-cell O-GlcNAcase by streptozotocin is the mechanism that accounts for its diabetogenic toxicity. N-nitroso-containing antibiotic, acting as a nitric oxide (NO) donor and vasorelaxant. Relaxes phenylephrine-contracted aortic rings at 10µM. Potent methylating agent for DNA.

Supplier: Cayman Chemical

Streptozocin

Supplier: Thermo Fisher Scientific

Streptozocin ≥97%

Supplier: MP Biomedicals

Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.