Supplier: TOSOH Bioscience

Hydrophobic interaction chromatography (HIC) is a powerful tool for the process purification of biomolecules. Five HIC ligands featuring different degrees of hydrophobicity and selectivity. The hydrophobicity of HIC resins increases through the ligand series.

Supplier: TOSOH Bioscience

Toyopearl resins can be used in organic solvents or mixtures of organic solvents and water. The compatibility of DMF with Toyopearl also permits the separation of hydrophobic substances such as polystyrenes.

Supplier: Thermo Fisher Scientific

Fluoraldehyde crystals are o-phthalaldehyde (OPA), a highly sensitive fluorescent derivatisation reagent for peptide or amino acid detection and quantitation in HPLC.

Supplier: TOSOH Bioscience

Bulk packing, PWXL Top-Off, 1 g wet resin, 10 µm

Supplier: HAMILTON BONADUZ

Polymer bulk packing material for anion exchange applications.

Supplier: MACHEREY-NAGEL

Polyamide 6 adsorbents for column chromatography.

Supplier: MACHEREY-NAGEL

Aluminium oxide adsorbents for column chromatography.

Supplier: MACHEREY-NAGEL

Hard granular magnesia silica gel: MgO (15,5 ±0,5%) SiO₂ (84,0 ±0,5%) Na₂SO₄ (≤1,0%) 60/100 mesh.

Supplier: MACHEREY-NAGEL

High purity silica phase for preparative HPLC.

Supplier: MACHEREY-NAGEL

Kieselguhr adsorbents for column chromatography.

Supplier: HAMILTON BONADUZ

Polymer bulk packing material for reversed phase applications.

Supplier: MACHEREY-NAGEL

Irregular silica phase for analytical HPLC.

Supplier: MACHEREY-NAGEL

High purity silica phase for HPLC.

Supplier: MACHEREY-NAGEL

High purity silica phase for HPLC.

Supplier: MACHEREY-NAGEL

Irregular silica phase for preparative HPLC.

Supplier: MERCK PRODUCTION CHEMICALS

The aluminium oxide crystal structure comprises octahedrally and tetrahedrally coordinated aluminium coupled by oxygen atoms. The aluminium oxide surface is covered by free hydroxyl groups. There are different acidic and basic centers (Broenstedt acid, Lewis acid and Lewis basic centers) that result in anion and cation exchange properties. Aluminium oxide exhibits a higher pH-stability than silica gel, especially in the alkaline range. Aluminium oxide occurs in various crystal modifications resulting in different pore diameters.

Supplier: MP Biomedicals

Lysozyme lysates harvested from cultures of Micrococcus lysodeikticus were attached to sepharose and used for affinity chromatography to isolate various bacteriolytic enzymes and it has also been used in a study to investigate the encapsulation of protein drugs in microparticles.

Supplier: MERCK PRODUCTION CHEMICALS

Micro-crystalline cellulose is a hydrophilic polysaccharide packing material preferred for the raw separation of amino acids and related compounds. Cellulose is also used for the gentle purification of bio-molecules. Because of the organic nature of cellulose, it can only be used in pre-swollen state and under gentle or hydrostatic pressure.

Supplier: MERCK PRODUCTION CHEMICALS

Composed of magnesium and silicon oxides in the approximate ratio of 85:15. This is a polar phase used for the chromatography of compounds such as steroids and alkaloids. This activity can be controlled by the activation temperature used.

Supplier: MP Biomedicals

Silica is highly porous and has a number of distinct crystalline forms (polymorphs) in addition to amorphous forms. It is used as a suspending and thickening agent in pharmaceuticals. It is also used in the extraction of DNA and RNA due to its ability to bind to the nucleic acids under the presence of chaotropes.

Supplier: Merck

LiChrosorb® is an irregular shaped silica sorbent. LiChrosorb® packing materials offer the compete programme of non-polar derivatives (RP-8, RP-18, RP-select B) and polar derivatives (Si 60 and Si 100).

Supplier: Merck

Superspher® 60 RP-8, 4 µm

Supplier: Merck

LiChrospher® RP-8 ADS, 25 µm

Supplier: VARIAN

The PL-SAX media are well suited for anion exchange HPLC separations of proteins, peptides, and deprotected synthetic oligonucleotides. Denaturing conditions of temperature, organic solvent, and high pH levels are used for the oligonucleotide separations.

Supplier: Merck

LiChrospher®, LiChrospher® 100 CN, 5 µm, 03

Supplier: Merck

In general, ion exchangers consist of a cross-linked polymer matrix with a uniform distribution of fixed ionic groups sited throughout the resin structure. These must be balanced by a similar number of ions of the opposite charge, (counter ions) to maintain electrical neutrality. Cation exchangers therefore, exchange and enrich only cations, anion exchangers only anions. In contrast adsorber resins have a non ionic, but depending on the structure, a somewhat polar character, and don't adsorb stoichiometrically both: anions, cations, as well as uncharged compounds.

Supplier: VARIAN

SepTech™ C18 bulk media, designed for high performance separations at high capacity. The two pore sizes, 60 Å and 150 Å, have been optimised to give high capacity for small molecules and larger natural molecules and peptides, respectively.

Supplier: VARIAN

The PLRP-S reversed phase HPLC media delivers the pure oligonucleotides (oligos) required for genomics applications, including quantitative PCR, microarrays, and gene synthesis assays.

Supplier: VARIAN

PL-SCX is a macroporous PS/DVB matrix with a very hydrophilic coating and strong cation exchange functionality. The manufacturing process is controlled to provide optimum density of strong cation-exchange moieties for analysing, separating, and purifying a wide range of biomolecules from small peptides to large proteins.