Hledali jste: Damnacanthal

Supplier: Enzo Life Sciences

Damnacanthal is a potent and selective inhibitor of p56lck tyrosine kinase. It inhibits p56lck autophosphorylation (IC50=17 nM) as well as phosphorylation of exogenous substrates (IC50=620 nM) in cell-free assays. Damnacanthal shows a 10-fold selectivity for p56lck over PKA and PKC and 40-fold selectivity over four receptor tyrosine kinases as well as 7–20-fold selectivity over the homologous enzymes p60src and p59fyn.