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UCN-01 (from Streptomyces sp. MST-AS5345) ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of protein kinase C (PKC) and cyclin-dependent kinases (CDKs) resulting in accumulation of cells in the G1 phase and induction of apoptosis. Enhances the cytotoxicity of other anticancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these agents.
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