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Fostriecin sodium salt (from Streptomyces pulveraceous subsp. fostreus) ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Antitumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong protein phosphatase 2A (PP2A) inhibitor (IC50=3.2nM). Weak inhibitor for PP1 (IC50=131µM). No apparent effect on PP2B. The binding site for fostriecin on PP2A is different from that of okadaic acid.
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