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Corning® Matrigel® Basement Membrane Matrix, Corning
  BDAA354248
 :  Corning
   Low Manufacturing Impact
 :  
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Corning® Matrigel® Basement Membrane Matrix, Corning
  BDAA354248
 :  Corning
   Low Manufacturing Impact
 :  

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  • Pk:
    10 mL
  • Description:
    Corning® Matrigel® Matrix, high concentration
  • Environmentally Preferable:
    Low Manufacturing Impact
  • Environmental certification:
    ISO 14001 - Bedford

 

 

Growth Factor Reduced (GFR) formulation is well suited for applications that require a more highly defined basement membrane preparation.

  • Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
  • Extensive PCR testing is performed to screen for a number of pathogens
  • Tested and found negative for bacteria, fungi, and mycoplasma
  • Protein concentrations determined by Lowry method
  • Endotoxin units measured by Limulus Amoebocyte Lysate assay
  • Matrigel Matrix gel stability tested for a period of 14 days at 37 °C
  • Biological activity determined for each lot using a neurite outgrowth assay.

Corning Matrigel matrix is a solubilised basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors.

Application
• Cell Growth and Differentiation
• Metabolism/Toxicology Studies
• Invasion Assays
In Vitro and In Vivo Angiogenesis Assays
In Vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice

Preparation and Storage
Store at –20 °C. Avoid multiple freeze-thaws.

Note: For research use only. Not intended for diagnostic or therapeutic procedures.

When warmed, the solution polymerizes to produce a biologically active matrix material resembling the mammalian cellular basement membrane. It is ideal for use with in vitro cell cultures of a broad range of cell types, including both primary and stem cell applications.