Supplier: US Biological

Anti-N-myc Downstream Regulated Gene 1 Protein Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: US Biological

Anti-MHC Class 1 Chain-related Gene A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Supplier: US Biological

Anti-MHC Class 1 Chain-related Gene A Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

Supplier: AAT BIOQUEST

Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Supplier: AAT BIOQUEST

Common reporter genes include beta-galactosidase, beta-glucuronidase and luciferase.

Supplier: Thermo Fisher Scientific

Microarray slides for in situ hybridisation and amplification with standard microscope slides.

Supplier: Merck Millipore (Oncogene)

Anti-Calcitonin Gene Related Peptide (CGRP) Rabbit Polyclonal Antibody

Supplier: Abcam

Mouse polyclonal to EBV Induced Gene 2/EBI2.

Supplier: EDVOTEK

In this experiment, students determine a pedigree for a family thought to be carriers of a mutation in their p53 genes. This is followed by a diagnostic agarose gel analysis to diagnose the state of the p53 gene in individual family members.

Supplier: Abcam

Rabbit monoclonal [EPR8766] to TRK fused gene.

Supplier: Abcam

Rabbit polyclonal to EBV Induced Gene 2/EBI2.

Supplier: ENZO LIFE SCIENCES

PATHO-GENE® HPV type 16/18/31/33/51 probe is a mixture of biotin-labeled HPV-16, HPV- 18, HPV-31, HPV-33 and HPV-51 specific probes in buffered formamide and hybridisation enhancers.

Supplier: EDVOTEK

Coronary heart disease and stroke are major causes of death in the Western world. Elevated blood cholesterol levels are a serious risk factor in both conditions. The genetic disease familial hypersholesterolemia (FH) causes an increase in blood levels of the bad form of cholesterol, low density lipoprotein (LDL). In untreated patients with the mutant FH gene, the condition can cause premature death. This experiment introduces the colorimetric enzymatic reaction which is the basis of the clinical cholesterol test. In addition, using agarose gel electrophoresis, students can analyse a simulated genetic screening for a disease.

Supplier: US Biological

Anti-MHC Class 1 Chain-related Gene A, B Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: 10F158]

Supplier: Bioss

Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organisation, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

Supplier: Bioss

Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organisation, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

Supplier: ANTIBODIES.COM

Rabbit monoclonal [ARC1882] antibody to TRK fused gene for WB with samples derived from human, mouse and rat.

Supplier: ANTIBODIES.COM

Rabbit polyclonal antibody to LAG3 for WB and ELISA with samples derived from human.

Supplier: Bioss

NPR2L is homologous to yeast nitrogen permease and is a candidate tumor suppressor, being a negative regulator of cell cycle. Most abundant in skeletal muscle, followed by brain, liver, and pancreas, with lower amounts in lung, kidney, placenta, and heart. Expressed in most lung cancer cell lines tested. There are two isoforms, produced by alternative splicing.

Supplier: Bioss

NPR2L is homologous to yeast nitrogen permease and is a candidate tumor suppressor, being a negative regulator of cell cycle. Most abundant in skeletal muscle, followed by brain, liver, and pancreas, with lower amounts in lung, kidney, placenta, and heart. Expressed in most lung cancer cell lines tested. There are two isoforms, produced by alternative splicing.

Supplier: US Biological

Anti-Calcitonin Gene-Related Peptide Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Calcitonin Gene Related Peptide Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

CALCB is a member of the calcitonin family. CALCB is produced in both peripheral and central neurons. It is a potent peptide vasodilator and can function in the transmission of pain. In the spinal cord, the function and expression of CGRP may differ depending on the location of synthesis. CALCB is derived mainly from the cell bodies of motor neurons when synthesised in the ventral horn of the spinal cord and may contribute to the regeneration of nervous tissue after injury.

Supplier: US Biological

Anti-T-Cell Death-Associated Gene 8 Rabbit Polyclonal Antibody

Supplier: Abcam

Rabbit monoclonal [EPR8766] to TRK fused gene - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR8765(2)(B)] to TRK fused gene - BSA and Azide free.

Supplier: US Biological

Anti-Calcitonin Gene-Related Peptide Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Protein Gene Product 9.5 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signalling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. ISG15 becomes conjugated to a diverse set of proteins after IFN-alpha/beta stimulation or microbial challenge. The functions or biochemical consequences ISG15 conjugation to proteins are not yet known, but it appears that this modification does not target proteins for proteasomal degradation. ISG15 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. Upon interferon treatment, ISG15 can be detected in both free and conjugated forms and is secreted from monocytes and lymphocytes where it can function as a cytokine. In the cell, ISG15 co-localises with intermediate filaments and ISGylation may modulate the JAK-STAT pathway or certain aspects of neurological disease.

Supplier: ANTIBODIES.COM

Recombinant T4 Gene 32 (from E. coli)