2192 Risultati per: "TMC HALLCREST"
Calpeptin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Calpain and cathepsin inhibitor
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BMOV ≥96% (by TLC)
Supplier: ENZO LIFE SCIENCES
Organic vanadium complex which acts as a potent insulin mimic.
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L-744,832 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expression and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.
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Anandamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].
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Apigenin ≥97% (by TLC)
Supplier: ENZO LIFE SCIENCES
Antioxidant and chemopreventive
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Virodhamine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor ligand.
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Ilimaquinone ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
ADP-ribosylation factor inhibitor
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Palmitoylethanolamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
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Latrunculin A ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ultra-pure; inhibits actin polymerization
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Methanandamide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor ligand
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DMOG ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.
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ML-9 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Selective inhibitor of MLC kinase (Ki=3.8 µM). Inhibits insulin-stimulated 2-deoxyglucose transport and PP-1 activation in adipocytes, possibly via an effect on MAP kinase or its activation. Useful PKB inhibitor (IC50=10-50 µM). Also known to inhibit PKA (IC50=20 µM) and S6 kinase (IC50=50 µM). Does not inhibit PI 3-kinase.
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Ac-WEHD-AMC
Supplier: ENZO LIFE SCIENCES
Substrate for caspase-1 and -5
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GW5074 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.
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Cerulenin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Fatty acid synthase inhibitor
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Aphidicolin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Reversible inhibitor of DNA polymerase a and d
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L-NASPA ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
L-NASPA is an antagonist of LPA-induced platelet aggregation and chloride conductance in Xenopus oocytes. In human breast carcinoma MDA-MB231 cells it is a potent LPA agonist.
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SB202190 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.
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Acitretin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Retinoic acid receptor ligand.
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Gabapentin ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ca²⁺ channel blocker
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Nome del fornitore: Integra
Nome del fornitore: EPPENDORF
Nome del fornitore: Integra
Nome del fornitore: Liebherr
Nome del fornitore: OZ BIOSCIENCES
Nome del fornitore: VWR Collection
Nome del fornitore: Corning
Nome del fornitore: SenseAnywhere
Nome del fornitore: NANOENTEK
Nome del fornitore: VWR Collection
Nome del fornitore: Integra
Nome del fornitore: Testo
Nome del fornitore: Testo
Nome del fornitore: Sartorius
Nome del fornitore: SenseAnywhere
Nome del fornitore: Quantabio