2189 Risultati per: "TMC HALLCREST"
GW5074 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.
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Cerulenin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Fatty acid synthase inhibitor
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Aphidicolin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Reversible inhibitor of DNA polymerase a and d
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L-NASPA ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
L-NASPA is an antagonist of LPA-induced platelet aggregation and chloride conductance in Xenopus oocytes. In human breast carcinoma MDA-MB231 cells it is a potent LPA agonist.
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SB202190 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis.
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Acitretin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Retinoic acid receptor ligand.
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Gabapentin ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Ca²⁺ channel blocker
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A-3 hydrochloride ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of cAMP- and cGMP-dependent protein kinase (PKA, Ki=4.3µM and PKG, Ki=3.8µM), protein kinase C (PKC, Ki=47µM), casein kinase I and II, and myosin light chain kinase (MLCK, Ki=7.4µM).
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5-Iodotubercidin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits ERK2 (Ki = 525nM). Also inhibits adenosine kinase (Ki = 30nM), CK1 and CK2 and insulin receptor kinase (IC50 ranging from 0.4-28µM).
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Decylubiquinone ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
MPTP inhibitor
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Misoprostol ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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AACOCF3 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid amide hydrolase (100% at 7.5 µM).
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(R)-Roscovitine ≥95% (by TLC)
Supplier: ENZO LIFE SCIENCES
CDK inhibitor
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Manoalide ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Phospholipase inhibitor
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Simvastatin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
HMG-CoA reductase inhibitor
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HBDDE ≥95% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits PKCα (IC50=43 µM) and PKCγ (IC50=50 µM) without inhibiting the δ, βI and βII isotypes.
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H-Arg-AMC·2HCl
Supplier: ENZO LIFE SCIENCES
Substrate for cathepsin H and aminopeptidases
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α-Hydroxytriazolam ≥96% (by TLC)
Supplier: ENZO LIFE SCIENCES
An active but short-lived metabolite of triazolam.