2189 Results for: "TMC HALLCREST"
H-7 dihydrochloride ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
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N-Arachidonylglycine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
FAAH inhibitor
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Midostaurin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.
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Dexamethasone ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Glucocorticoid receptor ligand
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U-75302 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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Lovastatin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
HMG-CoA reductase inhibitor
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Alamethicin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Mixture of alamethicin homologs. Membrane permeabilizing antibiotic. Applications include increasing [32P] incorporation into phosphatidylinositol 4-phosphate and permeabilization of sarcoplasmic reticulum vesicles. Causes fusion of lipid vesicles.
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Baicalein ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Lipoxygenase inhibitor
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Monastrol ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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(S)-Mephenytoin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cytochrome P450 substrate.
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2',5'-Dideoxyadenosine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Adenylate cyclase inhibitor
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Dorsomorphin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.
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Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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Kifunensine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.
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STAT3 Inhibitor V, Stattic ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation.
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(+/-)-Anatoxin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Nicotinic acetylcholine receptor ligand.
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Pravadoline ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor agonist.
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N-Arachidonoyldopamine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Activator of CB1 receptor and TRPV1
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4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).
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FH535 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits the recruitment of the co-activators β-catenin and GRIP1
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DICA ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.
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Supplier: EPPENDORF
Supplier: Integra
Supplier: Liebherr
Supplier: OZ BIOSCIENCES
Supplier: VWR Collection
Supplier: Corning
Supplier: SenseAnywhere
Supplier: Integra
Supplier: NANOENTEK
Supplier: VWR Collection
Supplier: Integra
Supplier: Testo
Supplier: Sartorius
Supplier: Quantabio