2189 Risultati per: "TMC HALLCREST"
IDE 2 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Induces stem cell differentiation.
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Palmityltrifluoromethylketone ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of both Ca2+-dependent cytosolic cPLA2 (IC50=45 µM) and Ca2+-independent phospholipases A2 iPLA2 (IC50=3.8 µM).
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Wortmannin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
PI3 kinase inhibitor
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SB216763 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.
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Chaetocin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Methyltransferase inhibitor
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DMNQ ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inducer of intracellular ROS generation.
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α-Hydroxyalprazolam ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Metabolite of alprazolam.
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Butyrolactone I ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
CDK inhibitor
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Baicalein ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Lipoxygenase inhibitor
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Alamethicin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Mixture of alamethicin homologs. Membrane permeabilizing antibiotic. Applications include increasing [32P] incorporation into phosphatidylinositol 4-phosphate and permeabilization of sarcoplasmic reticulum vesicles. Causes fusion of lipid vesicles.
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H-7 dihydrochloride ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits PKA (Ki=3.0μM), PKG (Ki=5.8μM), MLCK (Ki=97μM) and PKC (Ki=6μM). Also inhibits myosin light chain kinase. Induces apoptotic DNA fragmentation and cell death. Inhibits telomerase activity in treated NPC-076 cells. Cell permeable.
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Midostaurin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.
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Dexamethasone ≥99% (by TLC)
Supplier: ENZO LIFE SCIENCES
Glucocorticoid receptor ligand
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Lovastatin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
HMG-CoA reductase inhibitor
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U-75302 ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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N-Arachidonylglycine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
FAAH inhibitor
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Bisindolylmaleimide I ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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Monastrol ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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Dorsomorphin ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.
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Pravadoline ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cannabinoid receptor agonist.
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Kifunensine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.
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Ac-IETD-AMC
Supplier: ENZO LIFE SCIENCES
Caspase and granzyme substrate
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: Integra
: EPPENDORF
: Integra
: OZ BIOSCIENCES
: VWR Collection
: SenseAnywhere
: NANOENTEK
: VWR Collection
: Sartorius
: Quantabio