J.T.Baker® Endonuclease

J.T.Baker® Endonuclease Biotech Reagent meets the strictest cGMP standards and is designed for the degradation of both single stranded and double stranded DNA and RNA. J.T.Baker® Endonuclease Biotech Reagent is used to ensure host cell DNA impurities are removed; driving process efficiency by lowering viscosity and preventing aggregation. J.T.Baker® Endonuclease Biotech Reagent is an enzyme based upon the native endonuclease of Serratia marcescens, enabling rapid clearance of residual DNA and RNA during the production and purification of both recombinant proteins and viral vectors. Non-animal origin. Absence of proteolytic activity. The purity of materials in non-negotiable. J.T.Baker® Endonuclease Biotech Reagent acts to degrade and eliminate extraneous genetic material, ensuring the pristine quality of your final product.

• High purity, bioburden and endotoxin tested
• Rapid clearance of residual DNA and RNA
• Easily cleared in downstream processing, detectable by routine analytical methods
• 0.2 µm filtered solution
• Various size offerings
• Proven performance with J.T.Baker® Workflow solutions

Appearance: Passes Test
Identification: Passes Test
Purity by HPLC: ≥ 99%
Activity: ≥ 250 U/µL
Specific Activity: ≥ 1.1 x 10^6 U/mg
Protease: None detected
Total Aerobic Microbial Count: ≤ 10 cfu/ 100,000U
Total Yeast and Mold Count: ≤ 10 cfu/ 100,000U
Endotoxin: ≤ 0.25 EU/1,000U