Human/Mouse/Rat Recombinant GDF-11 (Animal free) (from E. coli)

Growth differentiation factor 11 (GDF-11), also known as bone morphogenetic protein 11 (BMP-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.

High Quality
Low Endotoxin
Affordable

: For research use only.

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Rat
Mouse
Condizioni di conservazione:
At or below –20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity assay: Alkaline phosphatase activity in ATDC5 cells, ED50 ≤100 ng/ml, Bioactivity ≥1,0×10⁴ units/mg
ID gene:
O95390 / Q9Z1W4 / Q9Z217
Ricostituzione:
Sterile 10 mM HCl at 0.1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
Y
Protein synonyms:
BMP-11
Protein/peptide name:
GDF-11
Purezza:
≥95%
Peso molecolare:
12,5/24,9 kDa
Sequenza:
NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic Acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT
Applicazioni testate:
Bioassay