Human/Mouse/Rat Recombinant BMP-2 (from E. coli)

Nome del fornitore: Shenandoah Biotechnology

Nome del fornitore: Shenandoah Biotechnology

Informazioni su questo articolo

Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.

High quality
Low endotoxin
Affordable

Caution: This product is for research use only and is not for use in humans.

Specifiche

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Rat
Mouse
Condizioni di conservazione:
At or below –20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity Assay: Alkaline phosphatase activity induced in ATDC-5 cells, ED₅₀ ≤250 ng/ml, Bioactivity ≥4,0×10³ units/mg
ID gene:
P12643 / P21274 / P49001
Ricostituzione:
Sterile water at 0,1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
Y
Protein synonyms:
BMP-2A
Protein/peptide name:
H/M/R BMP-2 (AF)
Purezza:
≥95%
Peso molecolare:
13,0/26,1 kDa
Sequenza:
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT
Applicazioni testate:
Bioassay