Horse Recombinant PDGF-BB (from E. coli)

New Product

Horse Recombinant PDGF-BB (from E. coli)

New Product

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatised tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

High quality
Low endotoxin
Affordable

: For research use only.

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Horse
Condizioni di conservazione:
–20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity Assay: NR6R 3T3 proliferation, ED₅₀ ≤30 ng/ml, Bioactivity ≥3,3×10⁴ units/mg
ID gene:
XP_005606703
Ricostituzione:
Sterile water at 0,1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
Y
Protein synonyms:
ODGF|GDGF
Protein/peptide name:
PDGF-BB (AF)
Purezza:
≥95%
Peso molecolare:
24,8 kDa
Sequenza:
MSLGSLAVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRHVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVGAARPVT
Livello di endotossine:
Low
Formulazione:
10 mM Sodium phosphate, pH 7,5
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT
Applicazioni testate:
Bioassay