Human/Mouse/Rat Recombinant Activin-A (from E. coli)

About this item

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin βA chains. Cleavage of the N-terminal propeptide renders the Activin protein biologically active. Human Activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline Activin A proteins.

High Quality
Low Endotoxin
Affordable

Caution: For research use only.

Specifications

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Rat
Mouse
Condizioni di conservazione:
At or below –20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity assay: Cytotoxicity of MPC-11 cells, ED50 ≤10 ng/ml, Bioactivity ≥1,0×10⁵ units/mg
ID gene:
P08476 / Q04998 / P18331
Ricostituzione:
Sterile water at 0.1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein synonyms:
Inhibin beta-1|FRP|FSH-releasing protein
Protein/peptide name:
Activin-A
Purezza:
≥95%
Peso molecolare:
13,1/26,2 kDa
Sequenza:
MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic Acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT
Applicazioni testate:
Bioassay