Specifications
- Conf:0,05 mg
- Tipo di enzima:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Sequenza tag:N-6 His tag
- Condizioni di conservazione:Store at −20 °C, stable for 6 months after receipt, please minimise freeze - thaw cycles
- Contenuto di endotossine:<0,1 ng/µg (1 IEU/µg) as determined by LAL test
- Nome dell'enzima:Aldehyde dehydrogenase 1-A3
- Sinonimi degli enzimi:Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6
- Purezza:>95% as determined by reducing SDS-PAGE
- Peso molecolare:57,5 kD
- Sequenza:Met1-Pro512
- Formulazione:Supplied as a 0,2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7,5, 20% Glycerol.
Specifications
About this item
Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolise a wide variety of aldehydes.
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag
ALDH1A3 specifically oxidises retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.