Specifications
- Tipo anticorpo:Primary
- Tipo di anticorpi:GOSR1/GS28
- Clonalità:Policlonale
- Coniugazione:Alexa Fluor® 680
- Ospite:Rabbit
- ImmunoChimica:Yes
- ImmunoFluorescenza:Yes
- Isotipo:IgG
- Reattività:Rat,Mouse
- Western blot:Yes
- Epitopo:151-250/250
- Forma:Liquid
- ID gene:9527
- Sinomini antigene:Golgi SNAP receptor complex member 1|P28|GOLIM2|28 kDa cis-Golgi SNARE p28|GOS28/P28|GOS-28|GOSR1|28 kDa Golgi SNARE protein|GOS28|GS28
- Modifica:Unmodified
- Tampone di conservazione:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Peso molecolare:29 kDa
- Temperatura di conservazione:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentrazione:1 µg/µl
- Temperatura di spedizione:4 °C
- Immunogeno:KLH conjugated synthetic peptide derived from human GOSR1/GS28
- Applicazioni testate:ICC
- Purificazione:Purified by Protein A
- Tipo di conf.:Vial
- Conf:100 µl
Specifications
About this item
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
Type: Primary
Antigen: GOSR1/GS28
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 151-250/250
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat