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Anti-NFKBIA/IKB alpha Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-NFKBIA/IKB alpha Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-1287R-A680
Supplier:  Bioss
Anti-NFKBIA/IKB alpha Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # BOSSBS-1287R-A680
Supplier:  Bioss

Specifications

  • Tipo anticorpo:
    Primary
  • Tipo di anticorpi:
    NFKBIA/IKB alpha
  • Clonalità:
    Policlonale
  • Coniugazione:
    Alexa Fluor® 680
  • Citometria a flusso:
    Yes
  • Ospite:
    Rabbit
  • ImmunoChimica:
    Yes
  • ImmunoFluorescenza:
    Yes
  • Isotipo:
    IgG
  • Reattività:
    Chicken,
    Human,
    Bovine,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Epitopo:
    1-120/314
  • Forma:
    Liquid
  • ID gene:
    18035
  • Sinomini antigene:
    Nfkbia|AI46215|IkappaBalpha|IkB-alpha|Nfkbi|Ikba|NF-kappa-B inhibitor alpha|I-kappa-B-alpha
  • Modifica:
    Unmodified
  • Tampone di conservazione:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Peso molecolare:
    36 kDa
  • Temperatura di conservazione:
    Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentrazione:
    1 µg/µl
  • Temperatura di spedizione:
    4 °C
  • Immunogeno:
    KLH conjugated synthetic peptide derived from mouse IKB alpha
  • Applicazioni testate:
    ICC
  • Purificazione:
    Purified by Protein A
  • Tipo di conf.:
    Vial
  • Conf:
    100 µl

Specifications

About this item

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localisation signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Type: Primary
Antigen: NFKBIA/IKB alpha
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1-120/314
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Bovine, Chicken