Human Recombinant IL-1RA (Animal free) (from E. coli)
Supplier: Shenandoah Biotechnology
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About this item
Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.
- High quality
- Low endotoxin
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IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.
Delivery: A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Condizioni di conservazione:−20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤1
- Attività biologica:Bioactivity assay: Inhibition human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- ID gene:P18510
- Ricostituzione:Sterile water at 0,1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:Y
- Protein synonyms:IL-1F3|IL1RN
- UniProtKB:P18510
- Protein/peptide name:IL-1RA
- Purezza:≥95%
- Peso molecolare:17,3 kDa
- Sequenza:MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
- Livello di endotossine:Low
- Formulazione:10 mM sodium phosphate, pH 7,5
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT
- Applicazioni testate:Bioassay
Specifications
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