Human recombinant BDNF (from E. coli)
About this item
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival.
- Animal-free
- Produced from genetically modified E. coli
- Noncovalent homodimeric protein, containing 120/240 amino acids
BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
4 Options Available Below
Product Details & Documents
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival.
- Animal-free
- Produced from genetically modified E. coli
- Noncovalent homodimeric protein, containing 120/240 amino acids
BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Documents
Literature reference - PubMed ID 24636514
Additional Product Details
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-01AF-10UG
- SHBT100-01AF-100UG
- SHBT100-01AF-500UG
- SHBT100-01AF-1MG
- Protein/peptide name:
- BDNF
- BDNF
- BDNF
- BDNF
- Protein synonyms:
- ANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2
- ANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2
- ANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2
- ANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Specie:
- Human
- Human
- Human
- Human
- Sorgente luminosa:
- E. coli
- E. coli
- E. coli
- E. coli
- Coniugazione:
- Non coniugato
- Non coniugato
- Non coniugato
- Non coniugato
- ID gene:
- P23560
- P23560
- P23560
- P23560
- Sequenza:
- MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
- Protease-free:
- N
- N
- N
- N
- Senza animali:
- Y
- Y
- Y
- Y
- Esente da nucleasi:
- N
- N
- N
- N
- Senza corriere:
- Y
- Y
- Y
- Y
- Privo di endotossine:
- N
- N
- N
- N
- Livello di endotossine:
- Low
- Low
- Low
- Low
- Contenuto di endotossine:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Attività biologica:
- Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mg
- Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mg
- Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mg
- Bioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mg
- Purezza:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grado:
- RUO
- RUO
- RUO
- RUO
- Forma:
- Lyophilised
- Lyophilised
- Lyophilised
- Lyophilised
- Formulazione:
- 0,1% Trifluoroacetic Acid (TFA)
- 0,1% Trifluoroacetic Acid (TFA)
- 0,1% Trifluoroacetic Acid (TFA)
- 0,1% Trifluoroacetic Acid (TFA)
- Peso molecolare:
- 13,6/27,3 kDa
- 13,6/27,3 kDa
- 13,6/27,3 kDa
- 13,6/27,3 kDa
- Ricostituzione:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Condizioni di conservazione:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Temperatura di spedizione:
- RT
- RT
- RT
- RT
- Applicazioni testate:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Tipo di conf.ConfAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT100-01AF-10UGProtein/peptide nameBDNFProtein synonymsANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP23560SequenzaMHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGRProtease-freeNSenza animaliYEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0,1Attività biologicaBioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mgPurezza≥95%GradoRUOFormaLyophilisedFormulazione0,1% Trifluoroacetic Acid (TFA)Peso molecolare13,6/27,3 kDaRicostituzioneSterile water at 0.1 mg/mlCondizioni di conservazione–20 °CTemperatura di spedizioneRTApplicazioni testateBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-01AF-100UGProtein/peptide nameBDNFProtein synonymsANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP23560SequenzaMHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGRProtease-freeNSenza animaliYEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0,1Attività biologicaBioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mgPurezza≥95%GradoRUOFormaLyophilisedFormulazione0,1% Trifluoroacetic Acid (TFA)Peso molecolare13,6/27,3 kDaRicostituzioneSterile water at 0.1 mg/mlCondizioni di conservazione–20 °CTemperatura di spedizioneRTApplicazioni testateBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-01AF-500UGProtein/peptide nameBDNFProtein synonymsANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP23560SequenzaMHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGRProtease-freeNSenza animaliYEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0,1Attività biologicaBioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mgPurezza≥95%GradoRUOFormaLyophilisedFormulazione0,1% Trifluoroacetic Acid (TFA)Peso molecolare13,6/27,3 kDaRicostituzioneSterile water at 0.1 mg/mlCondizioni di conservazione–20 °CTemperatura di spedizioneRTApplicazioni testateBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-01AF-1MGProtein/peptide nameBDNFProtein synonymsANON2|brain-derived neurotrophic factor|BNDF|brain derived neurotrophic factor|BULN2Protein/peptide typeRecombinantProtein functionCytokineSpecieHumanSorgente luminosaE. coliConiugazioneNon coniugatoID geneP23560SequenzaMHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGRProtease-freeNSenza animaliYEsente da nucleasiNSenza corriereYPrivo di endotossineNLivello di endotossineLowContenuto di endotossineEndotoxin LAL (EU/µg) ≤0,1Attività biologicaBioactivity assay: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6), ED50 ≤40 ng/ml, Bioactivity ≥2,5×10⁴ units/mgPurezza≥95%GradoRUOFormaLyophilisedFormulazione0,1% Trifluoroacetic Acid (TFA)Peso molecolare13,6/27,3 kDaRicostituzioneSterile water at 0.1 mg/mlCondizioni di conservazione–20 °CTemperatura di spedizioneRTApplicazioni testateBioassay
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