Mouse Recombinant TNF-A (from E. coli)
Supplier: Shenandoah Biotechnology
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About this item
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
- High quality
- Low endotoxin
- Affordable
Caution: This product is for research use only and is not for use in humans.
Specifications
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Mouse
- Condizioni di conservazione:–20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤0,1
- Attività biologica:Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- ID gene:P06804
- Ricostituzione:Sterile water at 0,1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:Y
- Protein synonyms:Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Protein/peptide name:TNF-A (AF)
- Purezza:≥95%
- Peso molecolare:17,4 kDa
- Sequenza:MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- Livello di endotossine:Low
- Formulazione:10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT
- Applicazioni testate:Bioassay
Specifications
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