Human Recombinant IL-31 (from E. coli)
Supplier: Shenandoah Biotechnology
Certificates
About this item
Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.
- High quality
- Low endotoxin
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IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.
Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Condizioni di conservazione:−20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤0.1
- Attività biologica:Bioactivity assay: STAT3 Activation in U-87 MG cells, ED50 ≤Detectable at ≤ 25 ng/ml, bioactivity ≥0
- ID gene:Q6EBC2
- Ricostituzione:Sterile water at 0,1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:N
- Protein synonyms:IL-31|Interleukin-31
- Protein/peptide name:IL31
- Purezza:≥95%
- Peso molecolare:15,8 kDa
- Sequenza:SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
- Livello di endotossine:Low
- Formulazione:20 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT
- Applicazioni testate:Bioassay
Specifications
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