Human recombinant FGF21 (from E. coli)
Supplier: Shenandoah Biotechnology
Certificates
About this item
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Specifications
- Coniugazione:Non coniugato
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Sorgente luminosa:E. coli
- Specie:Human
- Condizioni di conservazione:–20 °C
- Contenuto di endotossine:Endotoxin LAL (EU/µg) ≤0,1
- Attività biologica:Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- ID gene:Q9NSA1
- Ricostituzione:Sterile water at 0.1 mg/ml
- Privo di endotossine:N
- Senza corriere:Y
- Protease-free:N
- Senza animali:Y
- Protein synonyms:Fibroblast Growth Factor-21|FGF-21|FGFL
- Protein/peptide name:FGF21
- Purezza:≥95%
- Peso molecolare:19,5 kDa
- Sequenza:MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Livello di endotossine:Low
- Formulazione:10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- Esente da nucleasi:N
- Grado:RUO
- Temperatura di spedizione:RT
- Applicazioni testate:Bioassay
- Numero amminoacido:182
Specifications
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