Senescence kit

Senescence kit allows visualisation of aging cells and is ideal when cells in culture show abnormalities typical of the Hayflick limit after a long period of normal growth. The cells vary in size and shape, the cytoplasm begins to be granular with many cell inclusions and debris formed in the medium.

• Simple and rapid
• Ready to use
• Economical

Senescence goes with decreasing of proliferation potential, telomere shortening and impairment of cell function. During senescence in mammalian cells, an endogenous lysosomal β-galactosidase is over-expressed and is accumulated within the aging cells. The presence of this β-Gal activity is a marker of aging cell population in vitro.

Store kit at +4 °C.

Delivery information: Kit includes Fixing Buffer (125 ml), 10X PBS (75 ml), Staining Buffer (125 ml) and 25X Stock Solution of SA X-Gal (4×1 ml).